Book The Best Hotels in San Carlos Island, FL for 2026 from CA $86 - Fully Refundable Options

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Our top choices for San Carlos Island hotels

A spacious lobby with a high ceiling, a seating area with a sofa and chairs, a small round table, and a decorative wall with artwork.

1. Hampton Inn & Suites Fort Myers Beach/Sanibel Gateway

Fort Myers Beach

Chris

CA $147 total

includes taxes & fees

Nov 10 - Nov 11

An outdoor patio with tables and chairs, umbrellas, and a pool in the background.

2. Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Fort Myers Beach

Kimberly

CA $151 total

includes taxes & fees

Nov 16 - Nov 17

A spacious dining area with multiple tables and chairs, large windows, and a modern chandelier.

3. Residence Inn by Marriott Fort Myers Sanibel

Fort Myers

Lora

CA $161 total

includes taxes & fees

Nov 15 - Nov 16

A large, clear swimming pool with multiple lounge areas and palm trees.

4. Margaritaville Beach Resort Fort Myers

Fort Myers Beach

Lance

CA $350 total

includes taxes & fees

Nov 29 - Nov 30

A hotel pool area with multiple lounge chairs and umbrellas, surrounded by a fence and palm trees.

5. La Quinta Inn & Suites by Wyndham Ft. Myers-Sanibel Gateway

Fort Myers

Samantha

CA $126 total

includes taxes & fees

Nov 23 - Nov 24

A swimming pool with lounge chairs and umbrellas, surrounded by palm trees and a stone archway.

6. The Lighthouse Resort Inn & Suites

Fort Myers Beach

Shayne

CA $155 total

includes taxes & fees

Nov 16 - Nov 17

A balcony with wicker furniture, a view of a beach, and a clear sky.

7. Lani Kai Beachfront Resort

Fort Myers Beach

yeny

CA $235 total

includes taxes & fees

Dec 3 - Dec 4

A row of turquoise Adirondack chairs with umbrellas, a wooden deck, and a marina in the background.

8. Latitude 26 Waterfront Boutique Resort - Fort Myers Beach

Siesta Isle

Giovanna

CA $149 total

includes taxes & fees

Nov 9 - Nov 10

An outdoor seating area with a fire pit, outdoor furniture, and a covered patio.

9. TownePlace Suites by Marriott Fort Myers Gulf Coast

Fort Myers

Kevin

CA $150 total

includes taxes & fees

Nov 28 - Nov 29

A wooden deck with outdoor seating, a thatched-roof structure, and string lights.

10. Latitude 26 Waterfront Resort & Marina

Fort Myers Beach

Mitchel

CA $136 total

includes taxes & fees

Nov 9 - Nov 10

A hotel with a covered entrance, palm trees, and a well-maintained garden.

11. Homewood Suites by Hilton - Fort Myers

Villas

Anne

CA $173 total

includes taxes & fees

Nov 15 - Nov 16

A hotel room with two beds, a wooden headboard, a nightstand with a lamp, and a window with curtains.

12. Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

Sherri

CA $158 total

includes taxes & fees

Nov 12 - Nov 13

A beach with a variety of seashells and pebbles.

13. Sanibel Island Beach Resort

Mid Island

Elina

CA $353 total

includes taxes & fees

Nov 9 - Nov 10

A balcony with a table and chairs, large windows, and a view of the sea.

14. The Westin Cape Coral Resort At Marina Village

Pelican

Charles

CA $293 total

includes taxes & fees

Nov 15 - Nov 16

A modern hotel lobby with a wooden floor, leather armchairs, a round table, and a large abstract painting on the wall.

15. Extended Stay America Premier Suites - Fort Myers - Airport

Daniels Corridor

Isaura

CA $108 total

includes taxes & fees

Dec 6 - Dec 7

A modern dining area with wooden flooring, white chairs, and large windows offering a view of the beach.

16. Best Western Plus Beach Resort

Fort Myers Beach

Stacy

CA $341 total

includes taxes & fees

Nov 29 - Nov 30

17. Fairfield Inn & Suites by Marriott Ft. Myers/Cape Coral

Villas

Rick

CA $125 total

includes taxes & fees

Nov 22 - Nov 23

An outdoor patio area with a stone fire pit, seating, and string lights.

18. SpringHill Suites by Marriott Fort Myers Estero

Estero

Nail

CA $197 total

includes taxes & fees

Nov 13 - Nov 14

A modern hotel lobby with a seating area, a reception desk, and a dining area.

19. Hampton Inn & Suites - Cape Coral/Fort Myers Area, FL

Caloosahatchee

Joseph E.

CA $151 total

includes taxes & fees

Dec 3 - Dec 4

A hotel entrance with a sign reading 'Candlewood Suites' and a parking lot with a handicapped parking space.

20. Candlewood Suites Fort Myers Sanibel Gateway by IHG

South Fort Myers

James

CA $132 total

includes taxes & fees

Nov 10 - Nov 11

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Stay near popular San Carlos Island attractions

Ostego Bay Marine Science Center

8.4/10 (15 reviews)

You can spend time studying the exhibits at Ostego Bay Marine Science Center in Fort Myers Beach. Stroll along the beautiful beaches in this family-friendly area, or check out its lively bars.

See properties

Top San Carlos Island Hotel Reviews

Margaritaville Beach Resort Fort Myers

Fort Myers Beach

10/10 Excellent

Emily

Holiday Inn Express & Suites Ft Myers Beach-Sanibel Gateway by IHG

Fort Myers Beach

10/10 Excellent

Carlton

Best Western Plus Beach Resort

Fort Myers Beach

10/10 Excellent

Grace Carolyn

Holiday Inn Express Cape Coral-Fort Myers Area by IHG

Caloosahatchee

10/10 Excellent

We had a wonderful stay at Holiday Inn Express Cape Coral. The hotel was very clean, comfortable, and well maintained. A special thank you to Molly at the front desk. She was incredibly friendly, welcoming, and helpful from the moment we arrived. She made us feel truly valued as guests. We would also like to recognize the wonderful lady working in the breakfast area. She kept everything clean, fresh, and well organized, and she was always kind and attentive. The breakfast was excellent, and her...

Isaura